I know, I'm not ncalvo. My Tahoe Z71 came with 3.73. Every time I floor it, I die a lil inside.
I'll upgrade from 3.73 to 4.10 at my first convenient opportunity.
The pcmperformance tune was very helpful, the 4L60E is now much more enthusiastic about downshifting QUICKLY.
Still, 3.73 seems like the bare minimum axle gear for impatient leadfoots like myself.
If you are more of a laid back driver, 3.73 might suit you - I just disagree.
4.10 would actually improve metro / urban MpG by spending more time in 3rd than 3.73.
As for the highway, in 4th with the TCC locked up, 3.73 yields the following (255/70R18):
2250RpM = 82MpH
1750RpM = 64MpH
1250RpM = 46MpH
Since I don't spend much time cruising over 75MpH, 4.10 would suit me better on the highway too.
Hope this helps.