While AFM delete dongles and tunes do work as advertised (they disable AFM), they do not prevent collapsed lifter issues. The issue isn't AFM/DOD operation, the issue is the mechanical hardware itself. Preventing DOD with software does not remove the hardware in question. I only mention this because I've lost count of how many I know that went with AFM/DOD disabling dongle or tune, only top experience a collapse lifter anyway.
This hole AFM collapse lifter thing is hit or miss. Me personally, I'm in a 3rd AFM equipped Tahoe (5.3). This first I sold with 310,000 miles on it. No issues, was running smooth and quiet. I still own two 5.3L Tahoe's... one with just over 260,000 miles on it, the other is at 140,000. Neither experienced a lifter issue. Quiet and solid running. I did buy all three new myself, know them inside and out, and religiously changed oil when the DIC prompts me to do so. Always used Mobil 1 synthetic 5-30. My unscientific guess is that oil maintenance might have some bearing on it. I only feel this way because pretty much all those I now that have experience lifter collapses where a bit slack on their oil change maintenance. Again, not scientific, but it's all I got.
Having said all this, if I somehow manage to actually wear out one of the 5.3's, or experience a collapsed lifter, I'll probably just swap it with a crate 5.3 with DOD deleted (mechanically removed, lifters, cam, etc.).