The short of it is I want improved towing performance when I need it, without having to do more than check the tires, fluids, and top the tank up.
If hybridizing the heads and intake between my current LMG and the bottom end of either of the 6.0Ls (with the larger L96 Flex Fuel injectors)
can be tuned to run happily on the street on 87, but when I need to hitch up the 6000lb+ scout trailer all I do is fill the rest of the tank up with 93 or E85,
that's the sort of convenience I'm looking for.
To be redundant, that's EXACTLY what tuning is for.
What I'm worried about is taking the 9.6:1 static compression of the LY6 or L96 and upping it to 10.1:1, then towing with that.
LQ9 had 10:1 scr, basically made about as much power/torque as an LS1, on 87, and was rated to tow well over 6000lb (with 4.10, admittedly).
I will admit at this point that I put LM7 head 61cc chambers into the calculator the first time and had 10.7:1 that really worried me.
You worry too much. 10.7:1 is LFA/LZ1, both of which used 87 (although I don't know its tow rating).
Just in case you want to 'worry' less, YOUR 5.3L's heads are 65cc, not 61, so your scr would be lower than 10.7 for sure.
I'm still concerned about a long hill with my foot at or near the floor trying to hold 60mph on 10.1:1.
Again, LQ9 basically makes like an LS1 on 87 octane; with a few extra cubes, on 10.1:1 scr.
If you're really that concerned:
your tuner is not finished addressing your concerns, or your tune, yet
you can choose a slightly thicker GM OE gasket for lower scr
By the way, a blend of at least 33% E85 (meaning 66% 87 octane E10) guarantees at least 91 octane.
(Also, consider 3.73 instead of 3.42, so it'll spend more time in 6th & 5th & less time downshifting.)