I understand all of your points, and you are certainly free to do whatever you want to do, and I support your desire to have some project work on your truck.
If all you want is the chop sound, I don't know of any other way to achieve it, other than a cam swap. Other folks on this Forum who are much more knowledgeable than me in this area will chime in.
@Doubeleive @randeez @swathdiver @wjburken
I do want to correct you on your assumptions regarding the gear ratio change. In reality, the 4.10 gears will actually reduce the wear and tear on your motor and transmission, as the motor will spend less time in the low rpm's, where it is less efficient in load/rpms, and wasteful on gasoline. If you baby the truck, as you say, then the 4.10 gears will actually increase the longevity of the truck, AND improve gas mileage.
Regarding long tube headers, installed by themselves, they will do nothing, other than change the sound of the exhaust. An aftermarket muffler would be a better, cheaper, and easier installation alternative option, IMO.
If you want truck projects, then do maintenance projects on the truck to increase its longevity. At 280k miles, I would anticipate that there are several suspension related parts that could enjoy a refresh/replacement. Shocks/struts, control arms, ball joints, and all suspension bushings are all wear items that eventually need to be replaced.
In the engine bay, all heating and cooling hoses are likely on their last legs and should be replaced. Battery cables and ground straps may need replacement. All exposed electrical grounds could be inspected, cleaned and tightened.
Regarding motor longevity items, I don't know what your current oil pressure is, but if it is on the low side, you could replace the oil pump as a major project, and/or you could simply drop the oil pan and replace the O-ring on the oil pickup tube. If your oil pressure is good, then I would not recommend dropping the oil pan.
Hopefully, this gives you some things to think about, project-wise.