Care to expound upon that thought?
The days of a car running rough and it being either the carb or the cap and rotor are over. A tune up isn't a fix all any more. You have things like mass airflow sensors, oxygen sensors, MAP sensors, catalytic converters, evap systems, crankshaft and camshaft position sensors, etc.
In regards to alignment, we don't have front leaf springs any more where "toe and go" is acceptable. It's a torsion bar with eccentric adjustments for the upper control arm. You can't measure things like caster with a home setup. Camber, sure. but you start playing around with camber and it changes all of your other angles. Toe, good enough to get it to a shop but your margin of error there will be about +/- 2 degrees. Compared to the spec for these which have a tolerance of .2 degrees. And most guys worth their salt at an alignment place will strive to get you withing about .02 degrees of where you should be
Plus there's the issue of tires. The shop I worked at and most of the others in the area will deny you warranty coverage for your tires if you can't prove you've had a professional alignment done.
You could potentially do your own if you had some of the older --professional-- alignment tools (Not a tape measure and some chalk) but the cost of getting those will generally outweigh the cost of a lifetime alignment at a reputable chain. Then there's the issue of even having the basic ability to do it in your driveway. At a shop, all the wheels are placed on ball bearing slip plates that allow movement in in the XZ plane, so any adjustments made will be at ride height and you won't be fighting spring tension in the steering components and tires in your measurements.
I know we have an affinity for DIY stuff here on the forum. I get it. Believe me. I've rebuilt totaled cars in the driveway. But some things, there's no replacement for proper tools. Alignment is one of those few things that I don't have access to the proper equipment so I take it to someone who does.